Recombinant Human NUDT16, His-tagged

• Cat.No.: NUDT16-954H
• Product Overview: Recombinant human NUDT16 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: NUDT16 is nuclear nucleoside diphosphatase proteins localized within foci in the nucleolus and nucleoplasm. This is a RNA-decapping enzyme that binds specifically to U8 snoRNA. It can remove m7G and m227G caps from RNAs, rendering them substrates for 5'-3' exonucleases for degradation in vivo.
• Form: Liquid. In Phosphate Buffered Saline pH7.4 containing 10% glycerol.
• Molecular Weight: 23.4kDa (215aa) confirmed by MALDI-TOF.
• Purity: > 95% by SDS - PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MAGARRLELG EALALGSGWR HACHALLYAP DPGMLFGRIP LRYAILMQMR FDGRLGFPGG FVDTQDRSLE DGLNRELREE LGEAAAAFRV ERTDYRSSHV GSGPRVVAHF YAKRLTLEEL LAVEAGATRA KDHGLEVLGL VRVPLYTLRD GVGGLPTFLE NSFIGSAREQ LLEALQDLGL LQSGSISGLK IPAHH.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16 [ Homo sapiens ]
• Synonyms: nudix (nucleoside diphosphate linked moiety X)-type motif 16;FLJ31265; FLJ34034; FLJ36248; NUDT16; U8 snoRNA-decapping enzyme; nudix motif 16; U8 snoRNA-binding protein H29K; nucleoside diphosphate-linked moiety X motif 16; EC 3.6.1
• Gene ID: 131870
• mRNA Refseq: NM_152395
• Protein Refseq: NP_689608
• UniProt ID: Q96DE0
• Chromosome Location: 3q22.1
• Function: RNA binding; hydrolase activity; metal ion binding