Recombinant Human NTSR2 Protein, His-tagged

• Cat.No.: NTSR2-2516H
• Product Overview: Recombinant Human NTSR2 Protein (Ala37-Pro241) with a N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Ala37-Pro241
• Description: The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 23.6 kDa
  Accurate Molecular Mass: 16 kDa
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: NTSR2 neurotensin receptor 2 [ Homo sapiens (human) ]
• Official Symbol: NTSR2
• Synonyms: NTSR2; neurotensin receptor 2; neurotensin receptor type 2; NTR2; NT-R-2; neurotensin receptor, type 2; levocabastine-sensitive neurotensin receptor
• Gene ID: 23620
• mRNA Refseq: NM_012344
• Protein Refseq: NP_036476
• MIM: 605538
• UniProt ID: O95665