NTSR2
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Official Full Name
neurotensin receptor 2 -
Overview
The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a;phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this;receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However,;unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist;previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that;this receptor may be of physiological importance and that a natural agonist for the receptor may exist. -
Synonyms
NTSR2;neurotensin receptor 2;neurotensin receptor type 2;NTR2;NT-R-2;neurotensin receptor, type 2;levocabastine-sensitive neurotensin receptor
Recombinant Proteins
- Human
- Rat
- Cynomolgus
- E.coli
- Mammalian Cells
- Protein Conjugation
- HEK293
- GST
- His
- Avi
- Fc
Involved Pathway
NTSR2 involved in several pathways and played different roles in them. We selected most pathways NTSR2 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with NTSR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | ADRB3B,GABRA2,TAAR12F,TACR1,GCGR,GRM1,TAAR5,TAAR12G,PTGER1,TRHR |
Protein Function
NTSR2 has several biochemical functions, for example, G-protein coupled neurotensin receptor activity,G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NTSR2 itself. We selected most functions NTSR2 had, and list some proteins which have the same functions with NTSR2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein coupled receptor activity | GPR34L,GPR183,MTNR1BB,TACR1B,GPR97,HCAR1-2,OR2A4,OR7D2,NPFFR2.1,OR2H1 |
| G-protein coupled neurotensin receptor activity | NTSR1 |
Interacting Protein
NTSR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NTSR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NTSR2.
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