Recombinant Human NSD1 Protein, His-tagged

• Cat.No.: NSD1-143H
• Product Overview: Recombinant Human NSD1 protein, fused with N-terminal His tag, was expressed in Insect cell.

Specification

• Source: Insect cell
• Species: Human
• Tag: His
• Form: 50 mM Tris/HCl pH 7.5, 500 mM NaCl, 1 mM TCEP, 10% glycerol (v/v).
• Molecular Mass: 130.9 kDa
• Protein length: 1538-2696
• Purity: >90% by SDS-PAGE
• Storage: Store at -80°C. Thaw quickly and store on ice before use. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: NSD1 nuclear receptor binding SET domain protein 1 [ Homo sapiens ]
• Official Symbol: NSD1
• Synonyms: NSD1; nuclear receptor binding SET domain protein 1; Sotos syndrome , STO; histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific; ARA267; FLJ22263; KMT3B; H3-K36-HMTase; H4-K20-HMTase; lysine N-methyltransferase 3B; NR-binding SET domain-containing protein; androgen receptor-associated coregulator 267; androgen receptor coactivator 267 kDa protein; androgen receptor-associated protein of 267 kDa; nuclear receptor-binding SET domain-containing protein 1; STO; SOTOS; FLJ10684; FLJ44628; DKFZp666C163
• Gene ID: 64324
• mRNA Refseq: NM_022455
• Protein Refseq: NP_071900
• MIM: 606681
• UniProt ID: Q96L73
• Chromosome Location: 5q35
• Pathway: Androgen Receptor Signaling Pathway, organism-specific biosystem; Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem
• Function: androgen receptor binding; chromatin binding; estrogen receptor binding; histone methyltransferase activity (H3-K36 specific); histone methyltransferase activity (H3-K36 specific); histone methyltransferase activity (H4-K20 specific); ligand-dependent nuclear receptor binding; metal ion binding; methyltransferase activity; retinoic acid receptor binding; retinoid X receptor binding; thyroid hormone receptor binding; transcription cofactor activity; transcription corepressor activity; transferase activity; zinc ion binding