Recombinant Human NOTCH3 protein, hFc-tagged

• Cat.No.: NOTCH3-047H
• Product Overview: Recombinant Human NOTCH3 protein(Q9UM47)(Ala40-Glu467) is expressed from Expi293 with hFc tag at the C-terminal.

Specification

• Source: HEK293
• Species: Human
• Tag: Fc
• Form: Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
• Molecular Mass: The protein has a predicted MW of 71.53 kDa. Due to glycosylation, the protein migrates to 75-83 kDa based on Tris-Bis PAGE result.
• Protein length: Ala40-Glu467
• Endotoxin: Less than 1EU per μg by the LAL method.
• Purity: > 95% as determined by Tris-Bis PAGE
  > 95% as determined by HPLC
• Storage: -20 to -80°C for 12 months as supplied from date of receipt.
  -20 to -80°C for 3-6 months in unopened state after reconstitution.
  2-8°C for 2-7 days after reconstitution.
  Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid freeze-thaw cycles.
• Reconstitution: Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Gene Information

• Gene Name: NOTCH3 notch 3 [ Homo sapiens ]
• Official Symbol: NOTCH3
• Synonyms: NOTCH3; notch 3; CADASIL, Notch (Drosophila) homolog 3 , Notch homolog 3 (Drosophila); neurogenic locus notch homolog protein 3; CASIL; Notch homolog 3; CADASIL
• Gene ID: 4854
• mRNA Refseq: NM_000435
• Protein Refseq: NP_000426
• MIM: 600276
• UniProt ID: Q9UM47