Recombinant Human NNMT protein, His/SUMO-tagged

• Cat.No.: NNMT-149H
• Product Overview: Recombinant Human NNMT(2-264) fused with His/SUMO tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His&SUMO
• Protein Length: 2-264 a.a.
• Form: 50 mM Tris, pH 8.0, containing 500 mM sodium chloride, 5% glycerol, and 1 mM DTT
• Molecular Mass: 42.6 kDa
• Purity: ≥95% estimated by SDS-PAGE
• Unit Definition: One unit is defined as the amount of enzyme required to transfer one methyl group from S-adenosylmethionine to nicotinamide per minute using 100 µM nicotinamide at 25 centigrade.
• Stability: ≥6 months at -80 centigrade; avoid freeze/thaw cycles by aliquoting protein.

Gene Information

• Gene Name: NNMT nicotinamide N-methyltransferase [ Homo sapiens ]
• Official Symbol: NNMT
• Synonyms: NNMT; nicotinamide N-methyltransferase
• Gene ID: 4837
• mRNA Refseq: NM_006169
• Protein Refseq: NP_006160
• MIM: 600008
• UniProt ID: P40261
• Chromosome Location: 11q23.1
• Pathway: Biological oxidations, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Methylation, organism-specific biosystem; Nicotinate and nicotinamide metabolism, organism-specific biosystem; Nicotinate and nicotinamide metabolism, conserved biosystem; Phase II conjugation, organism-specific biosystem
• Function: methyltransferase activity; nicotinamide N-methyltransferase activity; transferase activity