Recombinant Human NKIRAS2, His-tagged

• Cat.No.: NKIRAS2-15859H
• Product Overview: Recombinant human NKIRAS2 protein, fused to His tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-191aa
• Description: NFKB inhibitor interacting Ras-like 2 (NKIRAS2), also known as KBRAS2, is similar to the Ras-like small GTPases that associate with IkappaB. These Ras-like proteins, NKIRAS1 and NKIRAS2, interact with the PEST domains of IkB alpha and IkB beta and decrease their rate of degradation. NKIRAS2 shows 71% identity to KBRAS1. NKIRAS2 is an inhibitor of the transcription factor NF-kappaB.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
• Molecular Mass: 24.0 kDa (215aa), confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMGKSCK VVVCGQASVG KTSILEQLLY GNHVVGSEMI ETQEDIYVGS IETDRGVREQ VRFYDTRGLR DGAELPRHCF SCTDGYVLVY STDSRESFQR VELLKKEIDK SKDKKEVTIV VLGNKCDLQE QRRVDPDVAQ HWAKSEKVKL WEVSVADRRSLLEPFVYLAS KMTQPQSKSA FPLSRKNKGS GSLDG
• Purity: 90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: NKIRAS2 NFKB inhibitor interacting Ras-like 2 [ Homo sapiens ]
• Official Symbol: NKIRAS2
• Synonyms: NKIRAS2; NFKB inhibitor interacting Ras-like 2; NFKB inhibitor interacting Ras like protein 2; NF-kappa-B inhibitor-interacting Ras-like protein 2; DKFZP434N1526; kappaB Ras2; KBRAS2; kappa B-Ras protein 2; I-kappa-B-interacting Ras-like protein 2; NFKB inhibitor interacting Ras-like protein 2; kappaB-Ras2; MGC74742; DKFZp434N1526
• Gene ID: 28511
• mRNA Refseq: NM_001144927
• Protein Refseq: NP_001138399
• MIM: 604497
• UniProt ID: Q9NYR9
• Chromosome Location: 17q21.31
• Pathway: TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem
• Function: GTP binding; GTPase activity; nucleotide binding