Recombinant Human NFKB2 Protein, MYC/DDK-tagged

• Cat.No.: NFKB2-815H
• Product Overview: Recombinant human NFKB2 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013].
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 96.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: nuclear factor kappa B subunit 2[ Homo sapiens ]
• Official Symbol: NFKB2
• Synonyms: LYT-10; LYT10; p52
• Gene ID: 4791
• mRNA Refseq: NM_001077493.1
• Protein Refseq: NP_001070961
• MIM: 164012
• UniProt ID: Q00653