Recombinant Human NFE2L2 protein, His & GST-tagged

• Cat.No.: NFE2L2-1917H
• Product Overview: Recombinant Human NFE2L2 aa. (Ser400~Lys603 (Accession # Q16236)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Description: This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 53.5kDa
• Protein length: Ser400~Lys603
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
• Reconstitution: Reconstitute in sterile ddH2O.
• Isoelectric Point: 8.7

Gene Information

• Gene Name: NFE2L2 nuclear factor, erythroid 2 like 2 [ Homo sapiens (human) ]
• Official Symbol: NFE2L2
• Synonyms: NFE2L2; nuclear factor, erythroid 2 like 2; NRF2; HEBP1; nuclear factor erythroid 2-related factor 2; nuclear factor erythroid-derived 2-like 2
• Gene ID: 4780
• mRNA Refseq: NM_001145412.3
• Protein Refseq: NP_001138884.1
• UniProt ID: Q16236