Recombinant Human Neuronal Calcium Sensor 1, His-tagged

• Cat.No.: NCS1-2353H
• Product Overview: Recombinant human NCS1 fused to His-tag at C-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. 22.9 kDa (198aa).

Specification

• Cat. No.: NCS1-2353H
• Description: Neuronal calcium sensor 1, also known as NCS1, is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. NCS1 is localized to neuronal cell bodies and axons throughout the brain and spinal cord. It is also expressed in glial cells and in neuroendocrine bovine adrenal chromaffin and PC12 cells. NCS1 is a regulatory protein involved in Ca++-dependent exocytosis of synaptic vesicles and dense core granules.
• Source: E.coli.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol.
• Purity: > 95% by SDS - PAGE.
• Concentration: 1 mg/ml (determined by BCA assay).
• Sequences Of Amino Acids: MGKSNSKLKP EVVEELTRKT YFTEKEVQQW YKGFIKDCPS GQLDAAGFQK IYKQ FF PFGD PTKFATFVFN VFDENKDGRI EFSEFIQALSVTSRGTLDEK LRWAFKLYDL DNDGYITRNE MLDIVDAIYQ MVGNTVELPE EENTPEKRVD RIFAMMDKNA DG KLTLQEFQ EGSKADPSIVQALSLYDGLV LEHHHHHH.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: NCS1 neuronal calcium sensor 1 [ Homo sapiens ]
• Synonyms: neuronal calcium sensor 1; FLUP; FREQ; DKFZp761L1223; NCS1; frequenin homolog; frequenin-like protein; frequenin-like ubiquitous protein
• Gene ID: 23413
• mRNA Refseq: NM_001128826
• Protein Refseq: NP_001122298
• MIM: 603315
• UniProt ID: P62166
• Chromosome Location: 9q34
• Function: calcium ion binding; protein binding