Recombinant Mouse Ncs1 Protein, Myc/DDK-tagged

• Cat.No.: Ncs1-4318M
• Product Overview: Purified recombinant protein of mouse full-length neuronal calcium sensor 1 (Ncs1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin. Stimulates PI4KB kinase activity. Involved in long-term synaptic plasticity through its interaction with PICK1. May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel.
• Molecular Mass: 21.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ncs1 neuronal calcium sensor 1 [ Mus musculus (house mouse) ]
• Official Symbol: Ncs1
• Synonyms: NCS1; neuronal calcium sensor 1; frequenin homolog; neuronal calcium sensor-1; Freq; Mfreq; NCS-1; AI836659; 9430075O15Rik; A730032G13Rik
• Gene ID: 14299
• mRNA Refseq: NM_019681
• Protein Refseq: NP_062655
• UniProt ID: Q8BNY6