Recombinant Human NEK2 Protein, His-tagged

• Cat.No.: NEK2-788H
• Product Overview: Recombinant Human NEK2(Lys125~Asn393) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 35.0kd
• Protein length: Lys125~Asn393
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: NEK2 NIMA (never in mitosis gene a)-related kinase 2 [ Homo sapiens ]
• Official Symbol: NEK2
• Synonyms: NEK2; NIMA (never in mitosis gene a)-related kinase 2; serine/threonine-protein kinase Nek2; HsPK 21; NEK2A; NLK1; nimA-like protein kinase 1; nimA-related protein kinase 2; HsPK21
• Gene ID: 4751
• mRNA Refseq: NM_001204182
• Protein Refseq: NP_001191111
• MIM: 604043
• UniProt ID: P51955