Recombinant Human NECTIN2 protein, His & T7-tagged

• Cat.No.: NECTIN2-7004H
• Product Overview: Recombinant Human NECTIN2 aa. (Pro76~Ala353 (Accession # Q92692)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Pro76~Ala353
• Description: This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 33.8kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 5.9.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: NECTIN2 nectin cell adhesion molecule 2 [ Homo sapiens (human) ]
• Official Symbol: NECTIN2
• Synonyms: NECTIN2; nectin cell adhesion molecule 2; HVEB; PRR2; CD112; PVRL2; PVRR2; nectin-2; herpesvirus entry protein B; poliovirus receptor-like 2; poliovirus receptor-related 2 (herpesvirus entry mediator B)
• Gene ID: 5819
• mRNA Refseq: NM_001042724.1
• Protein Refseq: NP_001036189.1
• UniProt ID: Q92692