Recombinant Human NCOA1, FLAG-tagged
Cat.No. : | NCOA1-29883TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 627-786 of Human KAT13A / SRC1 with Flag tag, Predicted MWt 18 kDa. |
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Species : | Human |
Source : | E.coli |
Tag : | Flag |
Protein Length : | 627-786 a.a. |
Description : | The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Conjugation : | FLAG |
Tissue specificity : | Widely expressed. |
Form : | Liquid |
Purity : | Immunogen affinity purified |
Storage buffer : | Preservative: NoneConstituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the SRC/p160 nuclear receptor coactivator family.Contains 1 basic helix-loop-helix (bHLH) domain.Contains 1 PAS (PER-ARNT-SIM) domain. |
Gene Name | NCOA1 nuclear receptor coactivator 1 [ Homo sapiens ] |
Official Symbol | NCOA1 |
Synonyms | NCOA1; nuclear receptor coactivator 1; bHLHe74; F SRC 1; KAT13A; NCoA 1; RIP160; SRC1; |
Gene ID | 8648 |
mRNA Refseq | NM_003743 |
Protein Refseq | NP_003734 |
MIM | 602691 |
Uniprot ID | Q15788 |
Chromosome Location | 2p23 |
Pathway | Adipogenesis, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Energy Metabolism, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; |
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Not For Human Consumption!
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