Recombinant Human NAMPT, His-tagged

• Cat.No.: NAMPT-311H
• Product Overview: Recombinant Human NAMPT(aa 1-491) ) fused a His-tag at the C-terminus was expressed in E. coli.

Specification

• Cat. No.: NAMPT-311H
• Description: This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10.
• Source: E. coli
• Molecular Mass: ~52kDa
• Formulation: Lyophilized. Salt-free.
• Purity: ≥90% as determined by SDS­PAGE
• Endotoxin Content: <1EU/μg purified protein (LAL test; Lonza).
• Concentration: 0.05 mg/ml
• Reconstitution: Reconstitute in distilled water.
• Storage: Working aliquots are stable for up to 3 months when stored at -20°C.
• OfficialSymbol: NAMPT
• Protein length: 1-491 a.a.

Gene Information

• Gene Name: NAMPT nicotinamide phosphoribosyltransferase [ Homo sapiens ]
• Synonyms: NAMPT; nicotinamide phosphoribosyltransferase; PBEF1, pre B cell colony enhancing factor 1; PBEF; visfatin
• Gene ID: 10135
• mRNA Refseq: NM_005746
• Protein Refseq: NP_005737
• MIM: 608764
• UniProt ID: P43490
• Chromosome Location: 7q22.3
• Pathway: Adipogenesis; Metabolism; Metabolism of vitamins and cofactors; Metabolism of water-soluble vitamins and cofactors; Nicotinamide salvaging
• Function: cytokine activity; nicotinamide phosphoribosyltransferase activity; nicotinate phosphoribosyltransferase activity; nicotinate-nucleotide diphosphorylase (carboxylating) activity; transferase activity, transferring glycosyl groups