Recombinant Human NAA10, His-tagged

• Cat.No.: NAA10-3610H
• Product Overview: Recombinant human NAA10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: NAA10 belongs to the acetyltransferase family. NAA10 interacts NAA15, HIF-1 with the ribosome. In its binding to HIF-1, NAA10 acts as a protein acetyltransferase by regulating its stability. In many cell lines, NAA10 is downregulated in response to hypoxia. NAA10 is expressed throughout the development of the brain.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 10% glycerol, 200mM NaCl
• Molecular Weight: 28.6kDa (255aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
• Purity: > 90% by SDS - PAGE
• Concentration: 1mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MNIRNARPED LMNMQHCNLL CLPENYQMKY YFYHGLSWPQ LSYIAEDENG KIVGYVLAKM EEDPDDVPHG HITSLAVKRS HRRLGLAQKL MDQASRAMIE NFNAKYVSLH VRKSNRAALH LYSNTLNFQI SEVEPKYYAD GEDAYAMKRD LTQMADELRR HLELKEKGRH VVLGAIENKV ESKGNSPPSS GEACREEKGL AAEDSGGDSK DLSEVSETTE STDVKDSSEA SDSAS
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit [ Homo sapiens ]
• Official Symbol: NAA10
• Synonyms: NAA10; TE2; ARD1; ARD1A; DXS707; MGC71248; N(alpha)-acetyltransferase 10, NatA catalytic subunit; N-alpha-acetyltransferase 10, NatA catalytic subunit; OTTHUMP00000026001; OTTHUMP00000026002; OTTHUMP00000064808; OTTHUMP00000064809; OTTHUMP00000180622; OTTHUMP00000180623; ARD1 homolog, N-acetyltransferase; ARD1 homolog A, N-acetyltransferase; N-acetyltransferase ARD1, human homolog of; N-terminal acetyltransferase complex ARD1 subunit homolog A; EC 2.3.1.88; EC=2.3.1.-
• Gene ID: 8260
• mRNA Refseq: NM_003491
• Protein Refseq: NP_003482
• MIM: 300013
• UniProt ID: P41227
• Chromosome Location: Xq28
• Function: N-acetyltransferase activity; contributes_to acetyltransferase activity; peptide alpha-N-acetyltransferase activity; protein binding; contributes_to ribosome binding; transferase activity