Recombinant Human MYOT Protein, His-tagged

• Cat.No.: MYOT-2496H
• Product Overview: Recombinant Human MYOT protein, fused to His-tagged at N-terminus, was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
• Form: 25 mM Tris, pH 8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl. Store at -80 Centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 55.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: MYOT myotilin [ Homo sapiens ]
• Official Symbol: MYOT
• Synonyms: LGMD1; LGMD1A; MFM3; TTID; TTOD
• Gene ID: 9499
• mRNA Refseq: NM_001135940
• Protein Refseq: NP_001129412
• MIM: 604103
• UniProt ID: Q9UBF9