Recombinant Human MYO7A Protein, His-tagged

• Cat.No.: MYO7A-2471H
• Product Overview: Recombinant Human MYO7A Protein (His9-Arg191) with a N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• ProteinLength: His9-Arg191
• Description: This gene is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. This gene encodes an unconventional myosin with a very short tail. Defects in this gene are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 24.5 kDa
  Accurate Molecular Mass: 26 kDa
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: MYO7A myosin VIIA [ Homo sapiens (human) ]
• Official Symbol: MYO7A
• Synonyms: MYO7A; myosin VIIA; DFNA11, DFNB2, myosin VIIA (Usher syndrome 1B (autosomal recessive, severe)), USH1B; unconventional myosin-VIIa; NSRD2; myosin-VIIa; myosin VIIA (Usher syndrome 1B (autosomal recessive, severe)); DFNB2; MYU7A; USH1B; DFNA11; MYOVIIA
• Gene ID: 4647
• mRNA Refseq: NM_000260
• Protein Refseq: NP_000251
• MIM: 276903
• UniProt ID: Q13402