Recombinant Human MYL12A, His-tagged

• Cat.No.: MYL12A-3606H
• Product Overview: Recombinant human MYL12A protein, fused to His-tag at N-terminus, was expressed inE.coli and purified by using conventional chromatography.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: MYL12A, also known as myosin regulatory light chain 12A,plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. This protein implicated in cytokinesis, receptor capping, and cell locomotion.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
• Molecular Weight: 22.4 kDa (195aa), confirmed by MALDI-TOF
• Purity: >90% by SDS - PAGE
• Concentration: 0.25 mg/ml (determined by Bradfordassay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGSHMSSKRT KTKTKKRPQR ATSNVFAMFD QSQIQEFKEA FNMIDQNRDG FIDKEDLHDM LASLGKNPTD EYLDAMMNEA PGPINFTMFL TMFGEKLNGT DPEDVIRNAF ACFDEEATGT IQEDYLRELL TTMGDRFTDE EVDELYREAP IDKKGNFNYI EFTRILKHGA KDKDD
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: MYL12A myosin, light chain 12A, regulatory, non-sarcomeric [ Homo sapiens ]
• Official Symbol: MYL12A
• Synonyms: MYL12A; MLCB; MRCL3; MRLC3; MYL2B; myosin, light chain 12A, regulatory, non-sarcomeric;myosin regulatory light chain 12A;MLC-2B;myosin RLC;OTTHUMP00000162243;myosin regulatory light chain 3;myosin regulatory light chain MRCL3;myosin regulatory light chain MRLC3;myosin regulatory light chain 2, nonsarcomeric;myosin, light polypeptide, regulatory, non-sarcomeric (20kD)
• Gene ID: 10627
• mRNA Refseq: NM_006471
• Protein Refseq: NP_006462
• UniProt ID: P19105
• Chromosome Location: 18p11.31
• Function: calcium ion binding; protein binding