Recombinant Human MYC Associated Factor X, His-tagged

• Cat.No.: MAX-2365H
• Product Overview: Recombinant human MAX protein, fused to His-tag at C-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. 19.3 kDa (168aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. In contrast to Myc, which is highly regulated during progression through the cell cycle, Max is highly stable and is much more abundant than Myc.
• Form: In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol.
• Purity: > 90% by SDS - PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MSDNDDIEVE SDEEQPRFQS AADKRAHHNA LERKRRDHIK DSFHSLRDSV PS LQG EKASR AQILDKATEY IQYMRRKNHT HQQDIDDLKR QNALLEQQVR ALE KARSSAQ LQTNYPSSDN SLYTNAKGST ISAFDGGSDS SSESEPEEPQ SRK KLR MEAS LEHHHHHH.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: MAX MYC associated factor X [ Homo sapiens ]
• Synonyms: MYC associated factor X; orf1; bHLHd4; bHLHd5; bHLHd6; bHLHd7; bHLHd8; MGC10775; MGC11225; MGC18164; MGC34679; MGC36767; MAX; protein max; myc-associated factor X; helix-loop-helix zipper protein; class D basic helix-loop-helix protein 4; MAX protein; Myc-associated factor X
• Gene ID: 4149
• mRNA Refseq: NM_002382
• Protein Refseq: NP_002373
• MIM: 154950
• UniProt ID: P61244
• Chromosome Location: 14q23
• Pathway: MAPK signaling pathway; Pathways in cancer; Small cell lung cancer
• Function: protein binding; protein heterodimerization activity; sequence-specific DNA binding; transcription coactivator activity; transcription cofactor activity; transcription factor activity