Recombinant Human MXD4 Protein, His-tagged

• Cat.No.: MXD4-569H
• Product Overview: Recombinant Human MXD4 fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
• Form: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 23.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: MXD4 MAX dimerization protein 4 [ Homo sapiens ]
• Official Symbol: MXD4
• Synonyms: MXD4; MAX dimerization protein 4; max dimerization protein 4; bHLHc12; MAD4; MST149; MSTP149; Mad4 homolog; max dimerizer 4; max-associated protein 4; class C basic helix-loop-helix protein 12; max-interacting transcriptional repressor MAD4
• Gene ID: 10608
• mRNA Refseq: NM_006454
• Protein Refseq: NP_006445
• UniProt ID: Q14582