Recombinant Human MUTYH, His-tagged

• Cat.No.: MUTYH-1116H
• Product Overview: Recombinant Human MUTYH protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 187-535aa
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: MUTYH mutY homolog (E. coli) [ Homo sapiens ]
• Official Symbol: MUTYH
• Synonyms: MUTYH; mutY homolog (E. coli); mutY (E. coli) homolog; A/G-specific adenine DNA glycosylase; MYH; CYP2C; MGC4416
• Gene ID: 4595
• mRNA Refseq: NM_001048171
• Protein Refseq: NP_001041636
• MIM: 604933
• UniProt ID: Q9UIF7
• Chromosome Location: 1p34.1
• Pathway: Base Excision Repair, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Base-Excision Repair, AP Site Formation, organism-specific biosystem; Base-free sugar-phosphate removal via the single-nucleotide replacement pathway, organism-specific biosystem; Cleavage of the damaged purine, organism-specific biosystem; DNA Repair, organism-specific biosystem
• Function: 4 iron, 4 sulfur cluster binding; NOT MutLalpha complex binding; NOT MutLbeta complex binding; MutSalpha complex binding; NOT MutSbeta complex binding; catalytic activity; endonuclease activity; hydrolase activity, acting on glycosyl bonds; metal ion bind