Recombinant Human musashi RNA-binding protein 2, His-tagged

• Cat.No.: MSI2-225H
• Product Overview: MSI2, 1-328aa, Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-328 a.a.
• Description: MSI2 is a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Two transcript variants encoding distinct isoforms have been identified for this gene. Recombinant human MSI2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
• Molecular Mass: 37.6 kDa (351aa), confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMEANGSQ GTSGSANDSQ HDPGKMFIGG LSWQTSPDSL RDYFSKFGEI RECMVMRDPT TKRSRGFGFV TFADPASVDK VLGQPHHELD SKTIDPKVAF PRRAQPKMVT RTKKIFVGGL SANTVVEDVK QYFEQFGKVE DAMLMFDKTT NRHRGFGFVT FENEDVVEKV CEIHFHEINN KMVECKKAQP KEVMFPPGTR GRARGLPYTM DAFMLGMGML GYPNFVATYG RGYPGFAPSY GYQFPGFPAA AYGPVAAAAV AAARGSGSNP ARPGGFPGAN SPGPVADLYG PASQDSGVGN YISAASPQPG SGFGHGIAGP LIATAFTNGY H
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: MSI2 musashi homolog 2 (Drosophila) [ Homo sapiens ]
• Official Symbol: MSI2
• Synonyms: MSI2; musashi homolog 2 (Drosophila); RNA-binding protein Musashi homolog 2; musashi-2; MSI2H; MGC3245; FLJ36569
• Gene ID: 124540
• mRNA Refseq: NM_138962
• Protein Refseq: NP_620412
• MIM: 607897
• UniProt ID: Q96DH6
• Chromosome Location: 17q23.2
• Pathway: mRNA surveillance pathway, organism-specific biosystem; mRNA surveillance pathway, conserved biosystem
• Function: nucleotide binding; poly(U) RNA binding; single-stranded RNA binding