Recombinant Human MTAP Protein, MYC/DDK-tagged

• Cat.No.: MTAP-2005H
• Product Overview: Recombinant human MTAP protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown. [provided by RefSeq, Jul 2008].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 31.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: MTAP methylthioadenosine phosphorylase [ Homo sapiens ]
• Official Symbol: MTAP
• Synonyms: BDMF; c86fus; DMSFH; DMSMFH; HEL-249; LGMBF; MSAP
• Gene ID: 4507
• mRNA Refseq: NM_002451
• Protein Refseq: NP_002442
• MIM: 156540
• UniProt ID: Q13126