Recombinant Human MTAP, GST-tagged

• Cat.No.: MTAP-29502TH
• Product Overview: Recombinant Human MTAP, fused with GST-tag at N-terminal, was expressed in E. coli.

Specification

• Description: This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: Liquid. 10% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0.
• Molecular Mass: 57 kDa
• Protein length: 2 to 283
• Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.

Gene Information

• Gene Name: MTAP methylthioadenosine phosphorylase [ Homo sapiens (human) ]
• Official Symbol: MTAP
• Synonyms: MTAP; BDMF; MSAP; DMSFH; LGMBF; DMSMFH; c86fus; HEL-249; methylthioadenosine phosphorylase; S-methyl-5'-thioadenosine phosphorylase; MTAPase; MTA phosphorylase; MeSAdo phosphorylase; epididymis luminal protein 249; 5'-methylthioadenosine phosphorylase; NP_002442.2; EC 2.4.2.28
• Gene ID: 4507
• mRNA Refseq: NM_002451
• Protein Refseq: NP_002442
• MIM: 156540
• UniProt ID: Q13126
• Chromosome Location: 9p21
• Pathway: Cysteine and methionine metabolism; Metabolism; Methionine salvage pathway
• Function: S-methyl-5-thioadenosine phosphorylase activity; phosphorylase activity