Recombinant Human MST1R Protein, His-tagged

• Cat.No.: MST1R-151H
• Product Overview: Recombinant Human macrophage stimulating 1 receptor(MST1R) protein, transcript variant 1 (NM_002447), with a His tag, was expressed in human cells.

Specification

• Description: This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.
• Source: Human Cells
• Species: Human
• Tag: His
• Form: Purified protein formulated in a sterile solution of TBS buffer, pH7.277, without any preservatives.
• Molecular Mass: 149.7 kDa
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
• Purity: >90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.

Gene Information

• Gene Name: MST1R macrophage stimulating 1 receptor (c-met-related tyrosine kinase) [ Homo sapiens ]
• Official Symbol: MST1R
• Synonyms: MST1R; macrophage stimulating 1 receptor (c-met-related tyrosine kinase); PTK8, PTK8 protein tyrosine kinase 8 , RON; macrophage-stimulating protein receptor; CD136; CDw136; p185-Ron; MSP receptor; RON variant E2E3; MST1R variant RON30; MST1R variant RON62; soluble RON variant 1; soluble RON variant 2; soluble RON variant 3; soluble RON variant 4; c-met-related tyrosine kinase; PTK8 protein tyrosine kinase 8; RON; PTK8
• Gene ID: 4486
• mRNA Refseq: NM_001244937
• Protein Refseq: NP_001231866
• MIM: 600168
• UniProt ID: Q04912