Recombinant Human MPP5 protein, His & T7-tagged

• Cat.No.: MPP5-833H
• Product Overview: Recombinant Human MPP5 aa. (Asn455~Arg675 (Accession # Q8N3R9)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: This gene encodes a member of the p55-like subfamily of the membrane-associated guanylate kinase (MAGUK) gene superfamily. The encoded protein participates in the polarization of differentiating cells, has been shown to regulate myelinating Schwann cells (PMID: 20237282), and is one of the components of the Crumbs complex in the retina. Mice which express lower levels of the orthologous protein have retinal degeneration and impaired vision (PMID: 22114289). Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His&T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 29.6kDa
• Protein length: Asn455~Arg675
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 7.2.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: MPP5 membrane palmitoylated protein 5 [ Homo sapiens (human) ]
• Official Symbol: MPP5
• Synonyms: PALS1; membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5); protein associated with Lin-7 1; protein associated with lin seven 1; stardust; MAGUK p55 subfamily member 5
• Gene ID: 64398
• mRNA Refseq: NM_001256550.1
• Protein Refseq: NP_001243479.1
• UniProt ID: Q8N3R9