MPP5

  • Official Full Name

    membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)

  • Overview

    This gene encodes a member of the p55-like subfamily of the membrane-associated guanylate kinase (MAGUK) gene;superfamily. The encoded protein participates in the polarization of differentiating cells, has been shown to regulate;myelinating Schwann cells (PMID: 20237282), and is one of the components of the Crumbs complex in the retina. Mice;which express lower levels of the orthologous protein have retinal degeneration and impaired vision (PMID: 22114289).;Multiple transcript variants encoding different isoforms have been found for this gene.

  • Synonyms

    MPP5;membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)

Recombinant Proteins

  • Human
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cell
  • HEK293
  • HEK293T
  • Wheat Germ
  • In Vitro Cell Free System
  • GST
  • His
  • His&T7
  • Non
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
MPP5-954H Recombinant Human MPP5, GST-tagged E.coli Human GST 1-341aa
MPP5-4464C Recombinant Chicken MPP5 Mammalian Cell Chicken His
MPP5-833H Recombinant Human MPP5 protein, His & T7-tagged E.coli Human His&T7 Asn455~Arg675
MPP5-4230HCL Recombinant Human MPP5 293 Cell Lysate HEK293 Human Non
MPP5-2957H Recombinant Human MPP5 Protein (Asn455-Arg676), His tagged E.coli Human His Asn455-Arg676
Mpp5-4126M Recombinant Mouse Mpp5 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
MPP5-5095H Recombinant Human MPP5 Protein (Asn455-Arg675), N-His tagged E.coli Human His Asn455-Arg675
MPP5-5513H Recombinant Human MPP5 Protein, GST-tagged Wheat Germ Human GST
MPP5-6329HF Recombinant Full Length Human MPP5 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 675 amino acids

    Involved Pathway

    MPP5 involved in several pathways and played different roles in them. We selected most pathways MPP5 participated on our site, such as Hippo signaling pathway,Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with MPP5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Hippo signaling pathway BMP2,APC2,FZD2,BMP8B,FZD9,ACTG1,DLG3,SMAD1,TEAD1,AREG
    Tight junction PARD6GB,RAB3B,MYH9A,MYL12.2,JAM2,MYH1E,MPP5A,CLDN11B,MAGI2,SHROOM1

    Protein Function

    MPP5 has several biochemical functions, for example, protein binding,protein domain specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MPP5 itself. We selected most functions MPP5 had, and list some proteins which have the same functions with MPP5. You can find most of the proteins on our site.

    Function Related Protein
    protein domain specific binding STRN4,MYO1D,YWHAQB,HIST2H4,FOXA1,RAB27A,THRA,ICA1L,SHROOM2,SLC34A2
    protein binding STX8,TSTD2,CCDC109A,DDX47,SMG5,CYTIP,ATXN10,ARL16,KCNA5,NCAPH2

    Interacting Protein

    MPP5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MPP5 here. Most of them are supplied by our site. Hope this information will be useful for your research of MPP5.

    AMOT;INADL;LIN7A;YAP1;SOCS4

    Resources

    Research Area

    Multiple Sclerosis and Myelin Related Molecules
    Apical-basal Polarity Effectors
    Tight Junctions

    References

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