Recombinant Human Monoamine Oxidase A

• Cat.No.: MAOA-708H
• Product Overview: Recombinant human monoamine oxidase A was expressed in Baculovirus infected BTI insect cells.

Specification

• Species: Human
• Source: Insect Cells
• Tag: Non
• Description: Monoamine oxidase A, also known as MAOA, is an enzyme which in humans is encoded by the MAOA gene. Monoamine oxidase A is an isozyme of monoamine oxidase. It preferentially deaminates norepinephrine (noradrenaline), epinephrine (adrenaline), serotonin, and dopamine (dopamine is equally deaminated by MAO-A and MAO-B). It is inhibited by clorgiline and befloxatone.
• Assay: ~2.5 mg per vial.
• Biochem/physiol Actions: MAO′s are proteins of the mitochondrial membrane. These enzymes are responsible for catalyzing oxidative deamination of endo- and xenobiotic amines. Substrate specificity differs for each isozyme.
• Shipped In: Dry ice.
• Storage Temp: −70°C.
• Personal Protective Equipment: Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US).

Gene Information

• Gene Name: MAOA monoamine oxidase A [ Homo sapiens ]
• Official Symbol: MAOA
• Synonyms: MAOA; monoamine oxidase A; amine oxidase [flavin-containing] A; MAO-A; monoamine oxidase type A; EC 1.4.3.4; Monoamine oxidase type A
• Gene ID: 4128
• mRNA Refseq: NM_000240
• Protein Refseq: NP_000231
• MIM: 309850
• UniProt ID: P21397
• Chromosome Location: Xp11.4-p11.3
• Pathway: Arginine and proline metabolism; Drug metabolism - cytochrome P450; Glycine, serine and threonine metabolism; Histidine metabolism; Metabolic pathways; Phenylalanine metabolism; Tryptophan metabolism; Tyrosine metabolism; Biological oxidations; Synaptic Transmission
• Function: amine oxidase activity; oxidoreductase activity; protein binding