Recombinant Human MLLT3 Protein, GST-tagged

• Cat.No.: MLLT3-5392H
• Product Overview: Human MLLT3 full-length ORF ( AAH36089, 1 a.a. - 568 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: GST
• Description: MLLT3 (MLLT3, Super Elongation Complex Subunit) is a Protein Coding gene. Diseases associated with MLLT3 include Acute Myeloid Leukemia With T(9;11)(P22;Q23) and Myeloid/Lymphoid Or Mixed Lineage Leukemia. Among its related pathways are Formation of HIV elongation complex in the absence of HIV Tat and Transcriptional misregulation in cancer. An important paralog of this gene is MLLT1.
• Molecular Mass: 88 kDa
• AA Sequence: MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSGSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS
• Applications: Antibody Production
  Functional Study
  Compound Screening
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 [ Homo sapiens ]
• Official Symbol: MLLT3
• Synonyms: MLLT3; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3; myeloid/lymphoid or mixed lineage leukemia (trithorax (Drosophila) homolog); translocated to, 3; protein AF-9; AF 9; AF9; YEATS3; YEATS domain-containing protein 3; ALL1-fused gene from chromosome 9 protein; myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 3; FLJ2035
• Gene ID: 4300
• mRNA Refseq: NM_004529
• Protein Refseq: NP_004520
• MIM: 159558
• UniProt ID: P42568