Recombinant Human Mitogen-activated Protein Kinase 8, His-tagged

Cat.No. : MAPK8-612H
Product Overview : Recombinant Human full length JNK1ß2 (MAPK8) produced ininsect cellsis fused to an N-terminal His-tag, 48 kDa.
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Species : Human
Source : Insect Cells
Tag : His
Description : JNK1 is the major c-Jun kinase after stimulation by inflammatory cytokines and environmental stresses. JNK phosphorylates nuclear receptors c-Jun, ATF-2, p53, Elk- and NFAT1.
Long Term Storage : -80°C.
Full Length : Full L.
Gene Name MAPK8 mitogen-activated protein kinase 8 [ Homo sapiens ]
Synonyms mitogen-activated protein kinase 8; JNK; JNK1; PRKM8; SAPK1; JNK1A2; JNK21B1/2; MAPK8; JNK-46; MAPK 8; MAP kinase 8; protein kinase JNK1; JUN N-terminal kinase; JNK1 beta protein kinase; JNK1 alpha protein kinase; c-Jun N-terminal kinase 1; stress-activated protein kinase 1; stress-activated protein kinase JNK1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 8 isoform JNK1 alpha1; Stress-activated protein kinase JNK1; OTTHUMP00000019552; EC 2.7.11.24
Gene ID 5599
mRNA Refseq NM_002750
Protein Refseq NP_002741
MIM 601158
UniProt ID P45983
Chromosome Location 10q11.22
Pathway Adipocytokine signaling pathway; Colorectal cancer; Epithelial cell signaling in Helicobacter pylori infection; ErbB signaling pathway; Fc epsilon RI signaling pathway; Focal adhesion; GnRH signaling pathway; Insulin signaling pathway; MAPK signaling pathway; NOD-like receptor signaling pathway; Neurotrophin signaling pathway; Pancreatic cancer; Pathways in cancer; Progesterone-mediated oocyte maturation; RIG-I-like receptor signaling pathway; Toll-like receptor signaling pathway; Type II diabetes mellitus; Wnt signaling pathway
Function ATP binding; JUN kinase activity; MAP kinase activity; kinase activity; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity

Not For Human Consumption!

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