Recombinant Human Mitogen-activated Protein Kinase 8

• Cat.No.: MAPK8-751H
• Product Overview: Recombinant Human Human Mitogen-activated Protein Kinase 8 Amino acidsM1-Q384, is expressed inE.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: Mitogen-activated protein kinase 8 is an enzyme that in humans is encoded by the MAPK8 gene. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development.
• Purification: Immobilized Metal Affinity Chromatography.
• Product Identity: JNK1 was confirmed as JNK1 by mass spectroscopy LC-ESI-MS/MS.
• MW: 44,292 Da.
• Storage Buffer: 50 mM Tris-HCl, pH 7.5; 100 mM NaCl, 5 mM DTT, 20% glycerol.
• Concentration: 0.513 μg/μl.
• Specific Activity: 2514 pmol/μg×min.
• Storage: -80°C. Avoid repeated freeze-thaw cycles!

Gene Information

• Gene Name: MAPK8 mitogen-activated protein kinase 8 [ Homo sapiens ]
• Synonyms:
  MAPK8; mitogen-activated protein kinase 8; JNK-46; JNK1 alpha protein kinase; JNK1 beta protein kinase; JUN N-terminal kinase; MAP kinase 8; MAPK 8; OTTHUMP00000019552; c-Jun N-terminal kinase 1; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; protein kinase JNK1; stress-activated protein kinase 1; stress-activated protein kinase JNK1; JNK; JNK1; PRKM8; SAPK1; JNK1A2; JNK21B1/2; EC 2.7.11.24
• Gene ID: 5599
• mRNA Refseq: NM_002750
• Protein Refseq: NP_002741
• MIM: 601158
• UniProt ID: P45983
• Chromosome Location: 10q11.22
• Pathway: Colorectal cancer; Epithelial cell signaling in Helicobacter pylori infection; ErbB signaling pathway; Focal adhesion; MAPK signaling pathway; NOD-like receptor signaling pathway; Pathways in cancer; Progesterone-mediated oocyte maturation; Type II diabetes mellitus; Wnt signaling pathway
• Function: ATP binding;JUN kinase activity; MAP kinase activity; kinase activity; protein serine/threonine kinase activity