Recombinant Human mitochondrial ribosomal protein L48, His-tagged

• Cat.No.: MRPL48-616H
• Product Overview: MRPL48, 29-212aa, Human, His tag, E.coli

Specification

• Description: Mammalian mitochondrial ribosomal proteins help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. Recombinant human MRPL48 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
• Molecular Mass: 23.1 kDa (207aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSSGEKPIY SVGGILLSIS RPYKTKPTHG IGKYKHLIKA EEPKKKKGKV EVRAINLGTD YEYGVLNIHL TAYDMTLAES YAQYVHNLCN SLSIKVEESY AMPTKTIEVL QLQDQGSKML LDSVLTTHER VVQISGLSAT FAEIFLEIIQ SSLPEGVRLS VKEHTEEDFK GRFKARPELE ELLAKLK
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)
• Protein length: 29-212 a.a.

Gene Information

• Gene Name: MRPL48 mitochondrial ribosomal protein L48 [ Homo sapiens ]
• Official Symbol: MRPL48
• Synonyms: MRPL48; mitochondrial ribosomal protein L48; 39S ribosomal protein L48, mitochondrial; CGI 118; L48MT; CGI-118; HSPC290; MRP-L48; FLJ17047; FLJ99260; MGC13323
• Gene ID: 51642
• mRNA Refseq: NM_016055
• Protein Refseq: NP_057139
• MIM: 611853
• UniProt ID: Q96GC5
• Chromosome Location: 11q13.4
• Function: protein binding; structural constituent of ribosome