MRPL48

  • Official Full Name

    mitochondrial ribosomal protein L48

  • Overview

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p.

  • Synonyms

    MRPL48;mitochondrial ribosomal protein L48;39S ribosomal protein L48, mitochondrial;CGI 118;39S ribosomal protein L48 mitochondrial;FLJ17047;FLJ99260;HSPC290;L48mt;MGC13323;MRP L48;CGI-118;MRP-L48

Recombinant Proteins

  • Human
  • Zebrafish
  • Chicken
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • In Vitro Cell Free System
  • GST
  • His
  • Non
Cat.# Product name Source (Host) Species Tag Protein Length Price
MRPL48-1011H Recombinant Human MRPL48, GST-tagged E.coli Human GST 1-212aa
MRPL48-147H Recombinant Human MRPL48, His-tagged HEK293 Human His 29-212 a.a.
MRPL48-2087Z Recombinant Zebrafish MRPL48 Mammalian Cell Zebrafish His
MRPL48-2219C Recombinant Chicken MRPL48 Mammalian Cell Chicken His
MRPL48-616H Recombinant Human mitochondrial ribosomal protein L48, His-tagged E.coli Human His 29-212 a.a.
MRPL48-4161HCL Recombinant Human MRPL48 293 Cell Lysate HEK293 Human Non
MRPL48-5591H Recombinant Human MRPL48 Protein, GST-tagged Wheat Germ Human GST
MRPL48-6432HF Recombinant Full Length Human MRPL48 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 212 amino acids

    Involved Pathway

    MRPL48 involved in several pathways and played different roles in them. We selected most pathways MRPL48 participated on our site, such as Mitochondrial translation,Mitochondrial translation elongation,Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL48 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Mitochondrial translation initiation MRPS31,MRPS36,MRPL42,DAP3,MRPL28,MRPL54,MRPL40,AURKAIP1,MRPS26,MRPS33
    Mitochondrial translation termination MTRF1L,MRPL28,GADD45GIP1,MRPL49,MRPS23,MRPL44,ICT1,MRPS27,MRPL53,MRPL40
    Mitochondrial translation elongation MRPS25,MRPS27,GADD45GIP1,TUFM,MRPL45,MRPS33,MRPL51,MRPS22,MRPS28,MRPS24
    Organelle biogenesis and maintenance MRPS36,BBS12,MRPL39,TTC21B,TTC30B,LZTFL1,MRPL28,MRPS34,MRPL44,TRIP11
    Mitochondrial translation MRPL37,MTFMT,MRPS28,MTIF3,MRPL51,ICT1,DAP3,PTCD3,MRPS25,MTRF1L

    Protein Function

    MRPL48 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL48 itself. We selected most functions MRPL48 had, and list some proteins which have the same functions with MRPL48. You can find most of the proteins on our site.

    Function Related Protein
    protein binding CACFD1,CETN2,AKAP6,CNOT7,DLL1,FCHO2,EXOSC8,S100A9,EPS8L1,CARD11

    Interacting Protein

    MRPL48 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL48 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL48.

    Kifc5b;ssrna_ag;AP4M1;Shoc2;SLC25A5;Eif3a;RPL10;CRK;YBX1;Cbx1;ICT1;Papss1;Rpl35;MRPL50;MRPL9;Bcas2;EXOSC4

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