Recombinant Human MITF Protein, His-tagged
Cat.No. : | MITF-2446H |
Product Overview : | Recombinant Human MITF Protein (Met1-Cys520) with a N-His tag was expressed in E. coli. |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Protein Length : | Met1-Cys520 |
Description : | The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 61.9 kDa Accurate Molecular Mass: 62 kDa |
Endotoxin : | <1.0 EU per 1µg (determined by the LAL method). |
Purity : | > 95% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name | MITF microphthalmia-associated transcription factor [ Homo sapiens (human) ] |
Official Symbol | MITF |
Synonyms | MITF; microphthalmia-associated transcription factor; Waardenburg syndrome, type 2A, WS2, WS2A; bHLHe32; homolog of mouse microphthalmia; MI; class E basic helix-loop-helix protein 32; WS2; WS2A; |
Gene ID | 4286 |
mRNA Refseq | NM_000248 |
Protein Refseq | NP_000239 |
MIM | 156845 |
UniProt ID | O75030 |
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Not For Human Consumption!
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