Recombinant Human minichromosome maintenance complex component 3 associated protein, GST-Tagged

• Cat.No.: MCM3AP-4372H
• Product Overview: GANP Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain having a total Mw of 43kDa. GANP is fused to a GST tag and is purified by proprietary chromatographic techniques.

Specification

• Species: Human
• Source: Human
• Tag: GST
• Description: GANP has a phosphorylation-dependent DNA-primase activity that is up-regulated in germinal center B regions/cells. GANP is related with MCM3, a protein essential for DNA replication. Increased expression of GANP is related with malignant transformation of melanocytes. GANP functions in the regulation of DNA repair during replication and survival of B cells.
• Form: GANP is supplied in 50mM Tris-Acetate, pH-7.5, 1mM EDTA and 20% Glycerol.
• Physical Appearance: Sterile filtered colorless solution.
• Storage: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
• Functions: DNA binding; protein binding; sequence-specific DNA binding transcription factor activity; zinc ion binding

Gene Information

• Gene Name: MCM3AP minichromosome maintenance complex component 3 associated protein [ Homo sapiens ]
• Official Symbol: MCM3AP
• Synonyms: MCM3AP; GANP; Protein GANP; KIAA0572; MAP80; FLJ44336; FLJ45306; minichromosome maintenance complex component 3 associated protein; MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) associated protein; minichromosome maintenance deficient (S. cerevisiae) 3-associated protein; human mRNA for MCM3 import factor; 80 kDa MCM3-associated protein; OTTHUMP00000115776; germinal center-associated nuclear protein; MCM3 import protein; MCM3 minichromosome maintenance deficient 3 associated protein; minichromosome maintenance deficient 3-associated protein; Protein GANP
• Gene ID: 8888
• mRNA Refseq: NM_003906
• Protein Refseq: NP_003897
• MIM: 603294
• UniProt ID: O60318
• Chromosome Location: 21q22.3