Recombinant Human MIF, His-tagged N-Terminus
Cat.No. : | MIF-24H |
Product Overview : | Recombinant human macrophage migration inhibitory factor (glycosylation-inhibiting factor), fused to His-tag at N-terminus, was cloned into anE. coliexpression vector and was purified to apparent homogeneity by using conventional column chromatography techniques. Macrophage Inducing Factor is a single, non-glycosylated, polypeptide chain containing amino acids from 1-114 and having a molecular mass of 16.6 kDa. |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Protein Length : | 1-114 a.a. |
Description : | The cytokine Macrophage migration inhibitory factor (MIF) has been identified to be secreted by the pituitary gland and the monocyte/macrophage and to play an important role in endotoxic shock. MIF has the unique property of being released from macrophages and T cells in response to physiological concentrations of glucocorticoids. The secretion of MIF is tightly regulated and decreases at high, anti-inflammatory steroid concentration. |
Physical Appearance : | 1mg/ml solution containing PBS pH-7.4. |
Amino Acid Sequence : | MRGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSMPMFIVNTNV PRASVPDGFL SELTQQLAQA TGKPPQYIAV HVVPDQLMAF GGSSEPCALC LHSIGKIGGA QNRSYSKLLC GLLAERLRIS PDRVYINYYD MNAANVGWNN STFA. |
Purity : | Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
Storage : | Liquid MIF although stable 14℃ for 1 week, should be stored desiccated below -18℃. Please prevent freeze-thaw cycles. |
Gene Name | MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) [ Homo sapiens ] |
Synonyms | MIF; macrophage migration inhibitory factor; GIF; GLIF; MMIF; phenylpyruvate tautomerase; glycosylation-inhibiting factor; EC 5.3.2.1; Glycosylation-inhibiting factor; Phenylpyruvate tautomerase |
Gene ID | 4282 |
mRNA Refseq | NM_002415 |
Protein Refseq | NP_002406 |
MIM | 153620 |
UniProt ID | P14174 |
Chromosome Location | 22q11.23 |
Pathway | Phenylalanine metabolism; Tyrosine metabolism |
Function | cytokine activity; dopachrome isomerase activity; isomerase activity; phenylpyruvate tautomerase activity;protein binding |
◆ Recombinant Proteins | ||
MIF-23H | Recombinant Human MIF protein, His-tagged | +Inquiry |
MIF-694C | Recombinant Cynomolgus MIF Protein, His-tagged | +Inquiry |
MIF-81H | Recombinant Human MIF, His-tagged | +Inquiry |
MIF-24H | Recombinant Human MIF, His-tagged N-Terminus | +Inquiry |
Mif-5716M | Recombinant Mouse Mif Protein (Pro2-Ala115), C-His tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
MIF-1917HCL | Recombinant Human MIF cell lysate | +Inquiry |
MIF-1884MCL | Recombinant Mouse MIF cell lysate | +Inquiry |
Not For Human Consumption!
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