Recombinant Human MIF, His-tagged N-Terminus

Cat.No. : MIF-24H
Product Overview : Recombinant human macrophage migration inhibitory factor (glycosylation-inhibiting factor), fused to His-tag at N-terminus, was cloned into anE. coliexpression vector and was purified to apparent homogeneity by using conventional column chromatography techniques. Macrophage Inducing Factor is a single, non-glycosylated, polypeptide chain containing amino acids from 1-114 and having a molecular mass of 16.6 kDa.
  • Specification
  • Gene Information
  • Related Products
  • Download
Species : Human
Source : E.coli
Tag : His
Protein Length : 1-114 a.a.
Description : The cytokine Macrophage migration inhibitory factor (MIF) has been identified to be secreted by the pituitary gland and the monocyte/macrophage and to play an important role in endotoxic shock. MIF has the unique property of being released from macrophages and T cells in response to physiological concentrations of glucocorticoids. The secretion of MIF is tightly regulated and decreases at high, anti-inflammatory steroid concentration.
Physical Appearance : 1mg/ml solution containing PBS pH-7.4.
Amino Acid Sequence : MRGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSMPMFIVNTNV PRASVPDGFL SELTQQLAQA TGKPPQYIAV HVVPDQLMAF GGSSEPCALC LHSIGKIGGA QNRSYSKLLC GLLAERLRIS PDRVYINYYD MNAANVGWNN STFA.
Purity : Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Storage : Liquid MIF although stable 14℃ for 1 week, should be stored desiccated below -18℃. Please prevent freeze-thaw cycles.
Gene Name MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) [ Homo sapiens ]
Synonyms MIF; macrophage migration inhibitory factor; GIF; GLIF; MMIF; phenylpyruvate tautomerase; glycosylation-inhibiting factor; EC 5.3.2.1; Glycosylation-inhibiting factor; Phenylpyruvate tautomerase
Gene ID 4282
mRNA Refseq NM_002415
Protein Refseq NP_002406
MIM 153620
UniProt ID P14174
Chromosome Location 22q11.23
Pathway Phenylalanine metabolism; Tyrosine metabolism
Function cytokine activity; dopachrome isomerase activity; isomerase activity; phenylpyruvate tautomerase activity;protein binding

Not For Human Consumption!

Inquiry

  • Reviews
  • Q&As

Customer Reviews (0)

Write a review

Q&As (0)

Ask a question

Ask a Question for All MIF Products

Required fields are marked with *

My Review for All MIF Products

Required fields are marked with *

0

Inquiry Basket

cartIcon