Recombinant Human MICU1 Protein, His-tagged

• Cat.No.: MICU1-1227H
• Product Overview: Recombinant human MICU1 protein, fused to His tag at N-terminus, was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013].
• Form: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
• Molecular Mass: 54.4 kDa
• Purity: >50 ug/mL as determined by microplate BCA method
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: MICU1 mitochondrial calcium uptake 1 [ Homo sapiens ]
• Official Symbol: MICU1
• Synonyms: CALC; CBARA1; EFHA3; MPXPS
• Gene ID: 10367
• mRNA Refseq: NM_001195518
• Protein Refseq: NP_001182447
• MIM: 605084
• UniProt ID: Q9BPX6