Recombinant Human MDK

• Cat.No.: MDK-30202TH
• Product Overview: Recombinant Midkine (Human), a 13.4 kDa protein containing 123 amino acid residues including five intra-molecular disulfide bonds.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: Midkine is a retinoic acid-responsive, heparin-binding growth factor expressed in various cell types during embryogenesis. It promotes angiogenesis, cell growth, and cell migration. Midkine is also expressed in several carcinomas, suggesting that it may play a role in tumorigenesis, perhaps through its effects on angiogenesis (summary by Reynolds et al.
• Form: Lyophilised
• Storage: The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C.
• Sequences of amino acids: VAKKKDKVKK GGPGSECAEW AWGPCTPSSK DCGVGFREGT CGAQTQRIRC RVPCNWKKEF GADCKYKFEN WGACDGGTGT KVRQGTLKKA RYNAQCQETI RVTKPCTPKT KAKAKAKKGK GKD
• Sequence Similarities: Belongs to the pleiotrophin family.

Gene Information

• Gene Name: MDK midkine (neurite growth-promoting factor 2) [ Homo sapiens ]
• Official Symbol: MDK
• Synonyms: MDK; midkine (neurite growth-promoting factor 2); NEGF2; midkine; FLJ27379; MK
• Gene ID: 4192
• mRNA Refseq: NM_001012333
• Protein Refseq: NP_001012333
• MIM: 162096
• Uniprot ID: P21741
• Chromosome Location: 11p11.2
• Pathway: Glypican 2 network, organism-specific biosystem; Syndecan-4-mediated signaling events, organism-specific biosystem
• Function: growth factor activity; growth factor activity; heparin binding