Recombinant Human MAX, FLAG-tagged

• Cat.No.: MAX-28524TH
• Product Overview: Recombinant full length Human MAX with Flag tag; amino acids 1-160 , 19 kDa.

Specification

• Description: The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature for some of them is unknown.
• Conjugation: FLAG
• Source: E. coli
• Form: Liquid
• Purity: Immunogen affinity purified
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Protein length: 1-160

Gene Information

• Gene Name: MAX MYC associated factor X [ Homo sapiens ]
• Official Symbol: MAX
• Synonyms: MAX; MYC associated factor X; MAX protein; protein max; bHLHd4; bHLHd5; bHLHd6; bHLHd7; bHLHd8
• Gene ID: 4149
• mRNA Refseq: NM_002382
• Protein Refseq: NP_002373
• MIM: 154950
• Uniprot ID: P61244
• Chromosome Location: 14q23
• Pathway: C-MYC pathway, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cyclin A:Cdk2-associated events at S phase entry, organism-specific biosystem; Cyclin E associated events during G1/S transition, organism-specific biosystem; G1/S Transition, organism-specific biosystem
• Function: protein binding; protein complex binding; protein heterodimerization activity; protein homodimerization activity; sequence-specific DNA binding

Reviews

07/16/2023

Greatly improve the rate and selectivity of chemical reactions, and its scientific research value is incomparable.

05/14/2023

MAX has excellent labeling results and can be used for a wide range of experimental methods, such as fluorescent labeling.

06/11/2021

The high catalytic efficiency, high safety, and high expression level make the experimental results extremely confident.

Q&As

How to evaluate the potential of MAX proteins as drug targets?

Evaluating the potential of MAX proteins as drug targets can involve several aspects, including their expression levels in organisms, their role in biological processes, and their changes in disease. In addition, factors such as ease of drug development for this protein and potential drug side effects need to be considered.

What is the function of MAX proteins?

The function of MAX proteins may be related to their localization and structure within the cell. It may be a nuclear protein that regulates the transcription of specific genes by binding to DNA. In addition, it may also regulate processes such as cell signaling and cell proliferation by interacting with other proteins.

What are the effects of mutations or modifications in MAX proteins on organisms?

Mutations or modifications of MAX proteins may affect their function and thus on the organism. The specific effects may vary depending on the type and location of the mutation or modification and may involve various biological processes, such as growth and development, immune response, etc.

What biological processes does MAX protein play a role in?

MAX proteins may be involved in a variety of biological processes, including cell proliferation, cell differentiation, apoptosis, etc. It may influence tumorigenesis and progression by modulating these processes.

How is the expression level of MAX protein regulated?

The expression level of MAX protein may be regulated by a variety of factors, including gene transcription, translation, post-transcriptional modification, etc. Studying these regulatory mechanisms can help to understand the expression patterns of MAX proteins in organisms and their effects on biological processes.

How does MAX protein interact with other proteins?

MAX proteins may interact with other proteins to fulfill their functions. These interactions can involve various types of protein-protein interactions like electrostatic interactions, hydrogen bonding, etc. Understanding these interactions can help uncover the mechanism of action of MAX proteins in cells.