Recombinant Human MARK2 cell lysate

• Cat.No.: MARK2-1060HCL

Specification

• Species: Human
• Tag: Non
• Description: This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: MARK2 MAP/microtubule affinity-regulating kinase 2 [ Homo sapiens ]
• Official Symbol: MARK2
• Synonyms: MARK2; MAP/microtubule affinity-regulating kinase 2; ELKL motif kinase , EMK1; serine/threonine-protein kinase MARK2; ELKL motif kinase 1; PAR 1; Par1b; protein serine/threonine kinase; Ser/Thr protein kinase PAR 1B; serine/threonine kinase; PAR1 homolog b; Ser/Thr protein kinase PAR-1B; serine/threonine protein kinase EMK; EMK1; EMK-1; PAR-1; Par-1b; MGC99619
• Gene ID: 2011
• mRNA Refseq: NM_001039469
• Protein Refseq: NP_001034558
• MIM: 600526
• UniProt ID: Q7KZI7
• Chromosome Location: 11q13.1
• Pathway: LKB1 signaling events, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem; Wnt Signaling Pathway NetPath, organism-specific biosystem
• Function: ATP binding; kinase activity; lipid binding; magnesium ion binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; protein serine/threonine kinase activity; tau-protein kinase activity