Recombinant Human MAPRE1 Protein, DDK-tagged

• Cat.No.: MAPRE1-465H
• Product Overview: Recombinant Human MAPRE1 fused with DDK tag at C-terminal was expressed in Sf9 cells.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: Flag
• Description: The protein encoded by tHis gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. THis protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that tHis protein is involved in the regulation of microtubule structures and chromosome stability. THis gene is a member of the RP/EB family.
• Form: 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol
• Molecular Mass: 29.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: MAPRE1 microtubule-associated protein, RP/EB family, member 1 [ Homo sapiens ]
• Official Symbol: MAPRE1
• Synonyms: MAPRE1; microtubule-associated protein, RP/EB family, member 1; microtubule-associated protein RP/EB family member 1; adenomatous polyposis coli binding protein EB1; EB1; end-binding protein 1; APC-binding protein EB1; adenomatous polyposis coli-binding protein EB1; MGC117374; MGC129946
• Gene ID: 22919
• mRNA Refseq: NM_012325
• Protein Refseq: NP_036457
• MIM: 603108
• UniProt ID: Q15691