Recombinant Human MAPK13, GST-tagged

• Cat.No.: MAPK13-48H
• Product Overview: Recombinant full-length human p38delta was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.

Specification

• Description: This gene encodes a member of the mitogen-activated protein (MAP) kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The encoded protein is a p38 MAP kinase and is activated by proinflammatory cytokines and cellular stress. Substrates of the encoded protein include the transcription factor ATF2 and the microtubule dynamics regulator stathmin. Alternatively spliced transcript variants have been observed for this gene.
• Source: Sf9 insect cells using baculovirus
• Species: Human
• Tag: GST
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: ~65 kDa
• Purity: >80%
• Applications: Kinase Assay, Western Blot
• Stability: 1 yr at -70ºC from date of shipment.
• Storage: Store product at –70ºC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.2 ug/ul

Gene Information

• Gene Name: MAPK13 mitogen-activated protein kinase 13 [ Homo sapiens (human) ]
• Official Symbol: MAPK13
• Synonyms: MAPK13; mitogen-activated protein kinase 13; SAPK4; PRKM13; MGC99536; p38delta; stress-activated protein kinase 4; mitogen-activated protein kinase p38 delta; mitogen activated protein kinase 13; EC 2.7.11.24
• Gene ID: 5603
• mRNA Refseq: NM_002754
• Protein Refseq: NP_002745
• MIM: 602899
• UniProt ID: O15264
• Chromosome Location: 6p21.31
• Pathway: Adrenergic signaling in cardiomyocytes; Amyotrophic lateral sclerosis (ALS); Epithelial cell signaling in Helicobacter pylori infection
• Function: ATP binding; MAP kinase activity; protein binding; protein serine/threonine kinase activity