Recombinant Human MAP4K3 protein, MYC/DDK-tagged

• Cat.No.: MAP4K3-185H
• Product Overview: Recombinant Human MAP4K3 fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Description: This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 101.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 [ Homo sapiens ]
• Official Symbol: MAP4K3
• Synonyms: MAP4K3; mitogen-activated protein kinase kinase kinase kinase 3; RAB8IPL1; GLK; MAPKKKK3; MEK kinase kinase 3; MAPK/ERK kinase kinase kinase 3; germinal center kinase-like kinase; germinal center kinase-related protein kinase; MEKKK 3
• Gene ID: 8491
• mRNA Refseq: NM_003618
• Protein Refseq: NP_003609
• MIM: 604921
• UniProt ID: Q8IVH8
• Chromosome Location: 2p22.3
• Pathway: Insulin Signaling, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; TNF receptor signaling pathway, organism-specific biosystem
• Function: ATP binding; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; small GTPase regulator activity