Recombinant Human M6PR, Fc-tagged, Biotinylated

• Cat.No.: M6PR-637H
• Product Overview: The recombinant human M6PR-Fc is expressed as a 387 amino acid protein consisting of Thr27 - Glu182 region of M6PR (UniProt #P20645) and a C-terminal Fc fusion from human IgG1, which exists as a dimer under non-reducing condition.

Specification

• Species: Human
• Source: Human Cells
• Tag: Fc
• Protein Length: 27-182 a.a.
• Form: Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
• Molecular Mass: Calculated molecular mass 43.3 kDa; estimated by SDS-PAGE under reducing condition 55-60 kDa probably due to glycosylation
• Endotoxin: <0.1 eu="" per="" 1="" μg="" of="" purified="" recombinant="" protein="" determined="" by="" the="" lal="">
• Purity: >95% judged by SDS-PAGE under reducing condition
• Storage: The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: M6PR mannose-6-phosphate receptor (cation dependent) [ Homo sapiens ]
• Official Symbol: M6PR
• Synonyms: M6PR; mannose-6-phosphate receptor (cation dependent); cation-dependent mannose-6-phosphate receptor; Mr 46,000 Man6PR; CD Man-6-P receptor; small mannose 6-phosphate receptor; 46-kDa mannose 6-phosphate receptor; SMPR; MPR46; CD-MPR; MPR 46; MPR-46; FLJ32994
• Gene ID: 4074
• mRNA Refseq: NM_001207024
• Protein Refseq: NP_001193953
• MIM: 154540
• UniProt ID: P20645
• Chromosome Location: 12
• Pathway: Clathrin derived vesicle budding, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Lysosome Vesicle Biogenesis, organism-specific biosystem; Membrane Trafficking, organism-specific biosystem; Phagosome, organism-specific biosystem; Phagosome, conserved biosystem
• Function: mannose binding; mannose transmembrane transporter activity; receptor activity; transmembrane signaling receptor activity