Recombinant Human LYPLA1, His-tagged

• Cat.No.: LYPLA1-7739H
• Product Overview: Recombinant Human AcylProtein Thioesterase 1/APT1 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1Asp230) of Human APT1 fused with a His tag at the Cterminus.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: AcylProtein Thioesterase 1 (APT1) is lysophospholipase that belongs to the AB hydrolase 2 family. APT1 performs on biological membranes to regulate the multifunctional lysophospholipids. It hydrolyzes fatty acids from Sacylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS; in addition, it also has depalmitoylating activity and low lysophospholipase activity.
• Form: Supplied as a 0.2 μM filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 10% Glycerol, pH 8.0
• Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Notes: For research use only.
• Storage: Store at less than 20°C. stable for 6 months after receipt.Please minimize freezethaw cycles.

Gene Information

• Gene Name: LYPLA1 lysophospholipase I [ Homo sapiens ]
• Official Symbol: LYPLA1
• Synonyms: LYPLA1; lysophospholipase I; APT-1, LPL1, LYSOPLA, hAPT1; LPL-I
• Gene ID: 10434
• mRNA Refseq: NM_006330.2
• Protein Refseq: NP_006321.1
• MIM: 605599
• UniProt ID: O75608
• Chromosome Location: 8q11.23
• Pathway: Glycerophospholipid metabolism, organism-specific biosystem; Glycerophospholipid metabolism, conserved biosystem; Metabolism, organism-specific biosystem; Metabolism of nitric oxide, organism-specific biosystem; eNOS activation, organism-specific biosystem; eNOS activation and regulation, organism-specific biosystem
• Function: lysophospholipase activity; palmitoyl-(protein) hydrolase activity