Recombinant Human Lymphotoxin Alpha, His-tagged

• Cat.No.: LTA-311H
• Product Overview: Recombinant Human Tumor Necrosis Factor-b produced inE.Coliis a single, non-glycosylated, polypeptide chain containing 171 amino acids fragment (35-205) and having a molecular mass of 23.3kDa with an amino-terminal his tag. The TNF-b His is purified by standard chromatographic techniques.

Specification

• Cat. No.: LTA-311H
• Description: TNF-β is a potent multifunctional cytokine produced mainly by activated T and B lymphocytes. The protein has been shown to have a specific potent cytotoxic activity on tumor cells and a variety of other target cells as well as being a mediator of inflammation and immune function.
• Source: Escherichia Coli.
• Purity: Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE
• Physical Appearance: Sterile Filtered clear solution.
• Formulation: TNF-b His is supplied in 20mM BTP, 50Mm NaCl and 50% glycerol.
• Stability: Store at 4℃ if entire vial will be used within 2-4 weeks. Store, frozen at -20℃ for longer periods of time. Please avoid freeze thaw cycles.
• Protein length: 35-205 a.a.

Gene Information

• Gene Name: LTA lymphotoxin alpha (TNF superfamily, member 1) [ Homo sapiens ]
• Synonyms: LTA; lymphotoxin alpha (TNF superfamily, member 1); LT; TNFB; TNFSF1; lymphotoxin alpha; OTTHUMP00000165897; tumor necrosis factor beta; Tumor necrosis factor ligand superfamily member 1; TNF-beta; LT-alpha
• Gene ID: 4049
• mRNA Refseq: NM_000595
• Protein Refseq: NP_000586
• MIM: 153440
• UniProt ID: P01374
• Chromosome Location: 6p21.3
• Pathway: Antigen processing and presentation; Cytokine-cytokine receptor interaction; Type I diabetes mellitus
• Function: cytokine activity; tumor necrosis factor receptor binding