Recombinant Human LY96 protein, MYC/DDK-tagged

• Cat.No.: LY96-327H
• Product Overview: Recombinant Human LY96 fussed with MYC/DDK tag at C-terminal was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Source: HEK293 cells
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 18.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: LY96 lymphocyte antigen 96 [ Homo sapiens ]
• Official Symbol: LY96
• Synonyms: MD2; MD-2; ly-96; ESOP-1; lymphocyte antigen 96; myeloid differentiation protein-2; protein MD-2
• Gene ID: 23643
• mRNA Refseq: NM_015364
• Protein Refseq: NP_056179
• MIM: 605243
• UniProt ID: Q9Y6Y9
• Chromosome Location: 8q21.11
• Pathway: Activated TLR4 signalling, organism-specific biosystem; Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, organism-specific biosystem; Diseases associated with the TLR signaling cascade, organism-specific biosystem
• Function: coreceptor activity; lipopolysaccharide receptor activity; protein binding