Recombinant Human LPHN1 cell lysate

• Cat.No.: LPHN1-1029HCL

Specification

• Species: Human
• Tag: Non
• Description: This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: LPHN1 latrophilin 1 [ Homo sapiens ]
• Official Symbol: LPHN1
• Synonyms: LPHN1; latrophilin 1; latrophilin-1; CIRL1; KIAA0821; LEC2; CIRL-1; lectomedin-2; calcium-independent alpha-latrotoxin receptor 1; CL1
• Gene ID: 22859
• mRNA Refseq: NM_001008701
• Protein Refseq: NP_001008701
• UniProt ID: O94910
• Chromosome Location: 19p13.2
• Pathway: GPCRs, Class B Secretin-like, organism-specific biosystem
• Function: G-protein coupled receptor activity; latrotoxin receptor activity; receptor activity; signal transducer activity; sugar binding; toxin binding