Recombinant Human LMNB1 cell lysate

Description :	The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.
Species :	Human
Size :	100 ul
Storage Buffer :	1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications :	Western Blot;
Tag :	Non

Gene Name	LMNB1 lamin B1 [ Homo sapiens ]
Official Symbol	LMNB1
Synonyms	LMNB1; lamin B1; lamin-B1; LMN; ADLD; LMN2; LMNB; MGC111419;
Gene ID	4001
mRNA Refseq	NM_001198557
Protein Refseq	NP_001185486
MIM	150340
UniProt ID	P20700
Chromosome Location	5q23.2
Pathway	Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; Breakdown of the nuclear lamina, organism-specific biosystem; Caspase cascade in apoptosis, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem;
Function	phospholipase binding; structural molecule activity;